149263-94-5 , 6-甲基-2-吡啶基-2-乙酰氨基-beta-D-硫代葡萄糖苷, CAS:149263-94-5

149263-94-5 , 6-Methyl-2-pyridinyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside,
6-甲基-2-吡啶基-2-乙酰氨基-beta-D-硫代葡萄糖苷,
Cas:149263-94-5
C14H20N2O5S / 328.39
MFCD18642965

6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside

6-甲基-2-吡啶基-2-乙酰氨基-beta-D-硫代葡萄糖苷,

The 6-Methyl-2-pyridyl 2-acetamido-2-deoxy-b-D-thioglucopyranoside is a chloride salt that has been used in the laboratory to develop an analytical method for the determination of glucose in urine samples. The bioavailability of 6MP is low and it is excreted by renal filtration, so this compound has been used as a marker for renal transplantation. Glomerular filtration rate (GFR) is reduced in diabetic patients, leading to a decrease in the amount of 6MP excreted. This drug can be administered orally or intravenously and has shown efficacy at low dose levels. Low doses have also been associated with decreased detection sensitivity due to its low level of excretion, which makes it an ideal candidate for use as a biomarker for chronic kidney disease. A chronic kidney disease animal model was used to study the effects on GFR and creatinine clearance rates.

CAS Number	149263-94-5
Product Name	N-((2S,3R,4R,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-((6-methylpyridin-2-yl)thio)tetrahydro-2H-pyran-3-yl)acetamide
IUPAC Name	N-[(2S,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(6-methylpyridin-2-yl)sulfanyloxan-3-yl]acetamide
Molecular Formula	C14H20N2O5S
Molecular Weight	328.39 g/mol
InChI	InChI=1S/C14H20N2O5S/c1-7-4-3-5-10(15-7)22-14-11(16-8(2)18)13(20)12(19)9(6-17)21-14/h3-5,9,11-14,17,19-20H,6H2,1-2H3,(H,16,18)/t9-,11-,12-,13-,14+/m1/s1
InChI Key	XUKXHOMZOIYNLR-FZGMBXNASA-N
SMILES	CC1=NC(=CC=C1)SC2C(C(C(C(O2)CO)O)O)NC(=O)C
Synonyms	6-Methyl-2-pyridyl N-acetyl-b-D-thioglucosamine; 6-Methyl-2-pyridinyl 2-(acetylamino)-2-deoxy-1-thio-beta-d-glucopyranoside
Canonical SMILES	CC1=NC(=CC=C1)SC2C(C(C(C(O2)CO)O)O)NC(=O)C
Isomeric SMILES	CC1=NC(=CC=C1)S[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)NC(=O)C

CAS No: 149263-94-5 Synonyms: 6-Methyl-2-pyridyl N-acetyl-b-D-thioglucosamineMPT-NAG MDL No: MFCD18642965 Chemical Formula: C14H20N2O5S Molecular Weight: 328.39

上一个：24384-88-1 , 6-脱氧-6-氨基-1,2-异丙叉-alpha-D-呋喃葡萄糖盐下一个：64714-42-7 , 5-(2,3,4,6- O-四乙酰基-beta-D-半乳糖基)四