157707-92-1 , 邻硝基苯基-a-唾液酸苷,
2-O-(2-Nitrophenyl)-a-D-N-acetylneuraminic acid,
CAS:157707-92-1
C17H22N2O11 / 430.36
MFCD00214337
邻硝基苯基-alpha-唾液酸苷
2-O-(2-Nitrophenyl)-a-D-N-acetylneuraminic acid is a chromogenic substrate specifically designed for the detection and quantification of sialidase (neuraminidase) enzyme activity. Neuraminidases are enzymes that cleave sialic acid residues from glycoconjugates, and are produced by many microorganisms, including influenza viruses. Upon cleavage by sialidase, this substrate releases a yellow-colored 2-nitrophenol product, which can be easily monitored spectrophotometrically. This substrate is widely used in various applications, including enzyme kinetics studies, inhibitor screening, and the detection of bacterial and viral neuraminidases in clinical and environmental samples.
CAS Number | 157707-92-1 |
Product Name | 5-acetamido-4-hydroxy-2-(2-nitrophenoxy)-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic Acid |
IUPAC Name | 5-acetamido-4-hydroxy-2-(2-nitrophenoxy)-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid |
Molecular Formula | C17H22N2O11 |
Molecular Weight | 430.4 g/mol |
InChI | InChI=1S/C17H22N2O11/c1-8(21)18-13-10(22)6-17(16(25)26,30-15(13)14(24)11(23)7-20)29-12-5-3-2-4-9(12)19(27)28/h2-5,10-11,13-15,20,22-24H,6-7H2,1H3,(H,18,21)(H,25,26) |
InChI Key | HWBGFIGDTJBVQD-UHFFFAOYSA-N |
SMILES | CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)OC2=CC=CC=C2[N+](=O)[O-])O |
Canonical SMILES | CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)OC2=CC=CC=C2[N+](=O)[O-])O |
CAS No: 157707-92-1 Synonyms: ONP-a-NeuNAc MDL No: MFCD00214337 Chemical Formula: C17H22N2O11 Molecular Weight: 430.36 |
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