Cellopentaose, 纤维五糖

Cellotriose is a bifunctional sugar that can be chemically converted to cellobiose and D-cellopentaose. Cellotriose is a component of cellulose, which is the most abundant biopolymer on Earth. Cellotriose is a source of chitin, which is a major component of the exoskeleton of insects and crustaceans. The molecule has been observed using atomic force microscopy to have an amphiphilic nature, in that it has both hydrophobic and hydrophilic regions. Cellotriose has been synthesized in the laboratory for use as an artificial sweetener, but it does not taste as good as sucrose because it lacks the sweetness profile. When heated, cellotriose undergoes a color change from yellow to blue-green due to its ability to form hydrogen bonds with oxygen molecules. This property can be used as a colorimetric test for cellulase activity in solutions.

Cellopentaose is a complex carbohydrate molecule composed of five linked glucose units. It belongs to the group of oligosaccharides, which are carbohydrates that consist of a small number of linked sugar units. Cellopentaose has become the focus of recent research due to its potential applications in various fields, including biotechnology, medicine, and food sciences. This paper aims to provide a comprehensive overview of cellopentaose, its properties, synthesis, and biological activities. Additionally, it will explore current research trends that provide insights into future directions and potential implications of cellopentaose in various fields.

Definition and Background:

Cellopentaose is a type of oligosaccharide that is composed of five glucose units linked by β1-4 bonds. It is a linear molecule and has a molecular weight of 947.07 g/mol. Cellopentaose occurs naturally in the cell walls of plants such as cotton, wood, and cellulosic materials. However, it is challenging to isolate and purify cellopentaose from natural sources. Therefore, researchers have turned to chemical synthesis as a means of producing cellopentaose in large quantities.

Physical and Chemical Properties:

Cellopentaose is a white, crystalline powder, and it is soluble in water, but insoluble in most organic solvents. The melting point of cellopentaose is around 248-249 °C, and it decomposes when heated to around 350 °C. Cellopentaose is stable under neutral or slightly basic conditions, but it hydrolyzes under acidic conditions to yield shorter oligosaccharides or glucose monomers.

Synthesis and Characterization:

There are two main approaches to synthesizing cellopentaose: chemical and enzymatic methods. The chemical synthesis method involves the reaction of glucose derivatives with chemical reagents such as thioglycolic acid to form cellopentaose. The enzymatic synthesis involves using glycosyltransferases to catalyze the reaction of glucose monomers to form cellopentaose.

Analytical Methods:

Several analytical methods are used to characterize cellopentaose, including high-performance liquid chromatography (HPLC), mass spectrometry (MS), and nuclear magnetic resonance (NMR) spectroscopy. These techniques are useful in determining the purity, molecular weight, and structural characteristics of cellopentaose.

Biological Properties:

Cellopentaose has several biological activities, including prebiotic, anti-inflammatory, and anti-tumor effects. As a prebiotic, cellopentaose is not digested in the human gastrointestinal tract but serves as a substrate for beneficial gut microorganisms, such as Bifidobacteria and Lactobacilli. It also promotes the growth of these bacteria, which are responsible for various health benefits.

Toxicity and Safety in Scientific Experiments:

Studies have shown that cellopentaose is safe and does not exhibit toxicity. However, more studies are needed to establish its safety under different experimental conditions.

Applications in Scientific Experiments:

Cellopentaose has several potential applications in various fields, including biotechnology, medicine, and food sciences. In biotechnology, cellopentaose is used as a substrate to produce cellulose by bacterial cellulose synthase. In medicine, cellopentaose has anti-inflammatory and anti-tumor properties, and it is being investigated for use in cancer treatment and prevention. In food science, cellopentaose is used as a prebiotic to promote the growth of beneficial bacteria in the gut.

Current State of Research:

Currently, research on cellopentaose is focused on exploring its biological activities and potential applications in various fields. Many studies are investigating its anti-inflammatory and anti-tumor properties and its potential to serve as a prebiotic.

Potential Implications in Various Fields of Research and Industry:

Cellopentaose has several potential implications in various fields of research and industry. In biotechnology, cellopentaose can be used to produce biodegradable plastics and fuel. In medicine, cellopentaose can be used as a drug carrier to deliver therapeutic agents to specific target tissues. In food science, cellopentaose can be used as a prebiotic ingredient in functional foods to promote gut health.

Limitations and Future Directions:

There are several limitations to using cellopentaose, including its cost, difficulty in isolation and purification, and limited availability. Future research on cellopentaose should focus on developing more efficient and cost-effective methods for its synthesis and exploring its potential applications in various fields. Some potential future directions include investigating its potential as a drug carrier, exploring its antimicrobial properties, and developing new applications in the food industry.

Conclusion:

Cellopentaose is a complex carbohydrate molecule that has several potential applications in various fields, including biotechnology, medicine, and food sciences. It has demonstrated prebiotic, anti-tumor, and anti-inflammatory effects and exhibits no toxicity. Despite its limitations, cellopentaose is a promising molecule that warrants further investigation to explore its full potential. Future research on cellopentaose should focus on developing more efficient methods for its synthesis, exploring its potential as a drug carrier, and investigating its antimicrobial properties.

COA:

Product name: D-Cellopentaose

CAS: 2240-27-9    M.F.: C₃₀H₅₂O₂₆     M.W.: 828.7

Batch No: 20100312        Quantity: 5mg from 25mg