55324-97-5 , 6-氨基-6-脱氧-D-葡萄糖盐酸盐, CAS:55324-97-5
C6H14ClNO5 / 215.63
MFCD00051996
6-Amino-6-deoxy-D-glucose hydrochloride is a chromatographic agent that is used to detect and identify viruses. It is also used to study antiviral drugs and the virus life cycle. 6-Amino-6-deoxy-D-glucose hydrochloride has been shown to inhibit protein synthesis in animal cells infected with paramyxoviruses, which may be due to its ability to inhibit acetylation of proteins. This drug has also been shown to inhibit influenza virus replication in cell culture. 6-Amino-6-deoxy--D--glucose hydrochloride binds to the viral ribonucleic acid (RNA) and inhibits the replication of the virus by binding competitively to the RNA polymerase enzyme.
CAS Number | 55324-97-5 |
Product Name | 6-Amino-6-deoxy-D-glucose hydrochloride |
IUPAC Name | (2R,3S,4R,5R)-6-amino-2,3,4,5-tetrahydroxyhexanal;hydrochloride |
Molecular Formula | C6H14ClNO5 |
Molecular Weight | 215.63 g/mol |
InChI | InChI=1S/C6H13NO5.ClH/c7-1-3(9)5(11)6(12)4(10)2-8;/h2-6,9-12H,1,7H2;1H/t3-,4+,5-,6-;/m1./s1 |
InChI Key | QWHLASPBRRZDEV-VFQQELCFSA-N |
SMILES | C(C(C(C(C(C=O)O)O)O)O)N.Cl |
Canonical SMILES | C(C(C(C(C(C=O)O)O)O)O)N.Cl |
Isomeric SMILES | C([C@H]([C@H]([C@@H]([C@H](C=O)O)O)O)O)N.Cl |
CAS No: 55324-97-5,4460-60-0 Synonyms: 9-Amino-6-deoxy-D-glucopyranose HCl MDL No: MFCD00051996 Chemical Formula: C6H13NO5·HCl Molecular Weight: 215.63 |
COA:
Product name: 6-Amino-6-deoxy-D-glucose Hydrochloride
CAS: 55324-97-5,4460-60-0 M.F.: C6H14ClNO5 M.W.: 215.63
Items | Standards | Results |
Appearance | White or slightly yellow powder | Complies |
Solubility | Insoluble in CHCl3, easily soluble in water | Complies |
MS and NMR | Should comply | Complies |
Residue on ignition | Max. 0.5% | 0.1% |
Heavy metal | Max.50ppm | Complies |
TLC | Should be one spot | one spot |
Assay by TLC | Min. 98% | 99.2% |
References:
1. Reist EJ, et al., J. Am. Chem. Soc. 1960, 82, p2025
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