61278-30-6 ,D-葡萄糖二酸-1,4-内酯, D-Glucaric acid-1,4-lactone,1,4-GL,CAS:61278-30-6

61278-30-6 ,D-葡萄糖二酸-1,4-内酯,
D-Glucaric acid-1,4-lactone,
CAS:61278-30-6
C6H8O7·H2O / 210.14
MFCD00149334

D-葡萄糖二酸-1,4-内酯, D-Glucaric acid-1,4-lactone

D-Saccharic acid 1,4-lactone monohydrate (DSAL) has an ability to inhibit the activity of β-glucuronidase enzyme. It also potentially inhibits Klotho deglycosylation of excitatory amino acid transporters (EAATs) and peptide transporters (PEPTs).

D-Saccharic acid 1,4-lactone is an inhibitor of β-glucuronidase (IC50 = 45 µM for the human enzyme). It is commonly used as a standard in the development of novel inhibitors of β-glucuronidase. D-Saccharic Acid 1,4-lactone is also used to prevent the cleavage of glucuronides in plasma, serum, or urine by β-glucuronidase in samples.

CAS Number	61278-30-6
Product Name	(S)-2-((2S,3R,4R)-3,4-Dihydroxy-5-oxotetrahydrofuran-2-yl)-2-hydroxyacetic acid hydrate
IUPAC Name	(2S)-2-[(3R,4R)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetic acid;hydrate
Molecular Formula	C6H10O8
Molecular Weight	210.14 g/mol
InChI	InChI=1S/C6H8O7.H2O/c7-1-2(8)6(12)13-4(1)3(9)5(10)11;/h1-4,7-9H,(H,10,11);1H2/t1-,2-,3+,4?;/m1./s1
InChI Key	NPFKVZHSFSFLPU-QGBSHYGGSA-N
SMILES	C1(C(C(=O)OC1C(C(=O)O)O)O)O.O
Synonyms	1,4-Lactone-D-glucaric Acid Monohydrate;
Canonical SMILES	C1(C(C(=O)OC1C(C(=O)O)O)O)O.O
Isomeric SMILES	[C@H]1([C@H](C(=O)O[C@@H]1[C@@H](C(=O)O)O)O)O.O

CAS No: 61278-30-6 Synonyms: D-SaccharolactoneD-Saccharic acid 1,4-lactone monohydrate MDL No: MFCD00149334 Chemical Formula: C6H8O7·H2O Molecular Weight: 210.14

white to off-white crystalline powder

上一个：136345-68-1 ,2,3,5,6-四-O-乙酰基-D-古洛糖酸内酯, CAS: 1 下一个：132489-69-1 ,2-(乙酰基氨基)-2-脱氧-N-[[(苯基氨基)羰基]氧基]-