6363-53-7, D-(+)-麦芽糖单水合物,
D-(+)-Maltose monohydrate,
CAS:6363-53-7
C12H22O11 · H2O / 360.31
MFCD00149343
Maltose is a disaccharide found in plants and bacteria. It is a degradation product of starch in plants that accumulates in a circadian rhythm-, day length-, and temperature-dependent manner. Maltose is formed from starch by the action of β-amylase and is a source of glucose in bacteria and mammals.
Maltose monohydrate is commonly used as a tablet filler or excipient in pharmaceutical industry.
D-(+)-Maltose monohydrate is a type of disaccharide made from two glucose molecules. It is widely used in the food industry as a sweetener, and in the chemical industry as a starting material for the synthesis of various chemical compounds. This paper provides a comprehensive review of D-(+)-Maltose monohydrate, covering its definition, physical and chemical properties, synthesis, characterization, analytical methods, biological properties, toxicity and safety in scientific experiments, applications in scientific experiments, current state of research, potential implications in various fields of research and industry, limitations, and future directions.
Synthesis and Characterization:
D-(+)-Maltose monohydrate can be synthesized through a series of chemical reactions starting from glucose. The most common method of synthesis involves the enzymatic hydrolysis of starch using the enzyme alpha-amylase, followed by the purification of the resulting maltose using ion exchange chromatography or other purification methods. D-(+)-Maltose monohydrate can be characterized using various analytical methods, including high-performance liquid chromatography (HPLC), gas chromatography (GC), nuclear magnetic resonance (NMR) spectroscopy, and infrared (IR) spectroscopy.
Analytical Methods:
Several analytical methods can be used to determine the purity and concentration of D-(+)-Maltose monohydrate. HPLC is commonly used to separate and quantify the sugars in a sample of D-(+)-Maltose monohydrate, while GC is used to separate and quantify the individual glucose molecules. NMR spectroscopy and IR spectroscopy can be used to characterize the chemical structure of D-(+)-Maltose monohydrate.
Biological Properties:
D-(+)-Maltose monohydrate has several biological properties that make it important for various scientific and medical applications. It is a type of carbohydrate that can provide energy to cells, and is also used by certain bacteria as a source of carbon. However, excessive consumption of D-(+)-Maltose monohydrate can lead to health problems such as obesity, diabetes, and heart disease.
Toxicity and Safety in Scientific Experiments:
D-(+)-Maltose monohydrate is generally considered safe for use in scientific experiments. However, it is important to use it in appropriate quantities and concentrations, and to follow all safety guidelines when handling the substance.
Applications in Scientific Experiments:
D-(+)-Maltose monohydrate has several applications in scientific experiments. It can be used as a sweetener in media for the growth of cells or bacteria, and as a substrate for various enzymatic reactions. It can also be used as a starting material for the synthesis of various chemical compounds.
Current State of Research:
Research on D-(+)-Maltose monohydrate is ongoing, with several studies focused on its various applications in the food, pharmaceutical, and chemical industries. Researchers are also investigating the potential health benefits and risks associated with its consumption.
Potential Implications in Various Fields of Research and Industry:
D-(+)-Maltose monohydrate has potential implications in various fields of research and industry. It is widely used as a sweetener in the food industry and as a starting material for the synthesis of various chemical compounds in the chemical industry. It also has potential applications in the pharmaceutical industry as a drug delivery agent or as a component in drug formulations.
Limitations and Future Directions:
One limitation of D-(+)-Maltose monohydrate is its potential impact on human health when consumed in excessive quantities. Future research should focus on identifying safe levels of consumption and developing alternative sweeteners that are less harmful to human health. Other future directions include investigations into the use of D-(+)-Maltose monohydrate in drug delivery and its potential impacts on the environment.
Conclusion:
D-(+)-Maltose monohydrate is an important carbohydrate with various industrial and scientific applications. Its definition, physical and chemical properties, synthesis, characterization, analytical methods, biological properties, toxicity and safety in scientific experiments, applications in scientific experiments, current state of research, potential implications in various fields of research and industry, limitations, and future directions have been reviewed in this paper. As research on D-(+)-Maltose monohydrate continues, its various applications in the food, pharmaceutical, and chemical industries, as well as its potential health benefits and risks, will be better understood.
CAS Number | 6363-53-7 |
Product Name | D-(+)-Maltose monohydrate |
IUPAC Name | (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanal;hydrate |
Molecular Formula | C₁₂H₂₄O₁₂ |
Molecular Weight | 360.31 g/mol |
InChI | InChI=1S/C12H22O11.H2O/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12;/h1,4-12,14-21H,2-3H2;1H2/t4-,5+,6+,7+,8+,9-,10+,11+,12+;/m0./s1 |
InChI Key | HBDJFVFTHLOSDW-DNDLZOGFSA-N |
SMILES | C(C1C(C(C(C(O1)OC(C(CO)O)C(C(C=O)O)O)O)O)O)O.O |
Synonyms | 4-O-α-D-Glucopyranosyl-D-glucose Hydrate; 4-O-α-D-Glucopyranosyl-D-glucose Monohydrate; Maltobiose Hydrate; |
Canonical SMILES | C(C1C(C(C(C(O1)OC(C(CO)O)C(C(C=O)O)O)O)O)O)O.O |
Isomeric SMILES | C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@H]([C@@H](CO)O)[C@@H]([C@H](C=O)O)O)O)O)O)O.O |
CAS No: 6363-53-7,69-79-4 Synonyms: 4-O-a-D-Glucopyranosyl-D-glucopyranose monohydrateMaltose MDL No: MFCD00149343 Chemical Formula: C12H22O11·H2O Molecular Weight: 360.31 | In Stock ,国产现货高纯,白色结晶粉末. |
COA:
Name: D-(+)-Maltose monohydrate CAS: 6363-53-7,69-79-4
M.F.: C12H22O11 · H2O M.W.: 360.31 Batch No: 20121211 Quantity: 365kg
Items | Standards | Results |
Appearance | A white powder | Complies |
Solubility | Easily soluble in water. Clear and colorless solution | Complies |
MS and NMR | Should comply | Complies |
Specific rotation (C =4 inwater plus ammonium hydroxide at 20 degree) | +128° ~ +132° | +130.6° |
Water | 4% ~ 6% | 4.7% |
Glucose | Max. 1% | 0.12% |
Maltotriose | Max.1% | 0.45% |
Assay | Min. 98% | 99.3% |
References:
1. Zhang T, Marchant RE, Macromolecules 1994, No27, p7302-7308
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