361154-23-6 ,2-[(Azidoacety)amino]-2-deoxy-D-mannose,
Cas:361154-23-6
C8H14N4O6 / 262.22
2-[(叠氮乙酰)氨基]-2-脱氧-D-甘露糖,
N-Azidoacetylmannosamine, also called ManNAz and 2-[(2-azidoacetyl)amino]-2-deoxy-D-mannose, is a click reagent for metabolic labelling of ManNAc. The azide is able to react with an alkyne in a 1,3-dipolar cycloaddition reaction (click chemistry) to enable linking to a fluorescent probe or a biotin. N-Azidoacetylmannosamine has been used in the chemical modification of glycoproteins to improve their in vivo efficacy and to label them for detection.
CAS Number | 361154-23-6 |
Product Name | ManNaz |
IUPAC Name | 2-azido-N-[2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide |
Molecular Formula | C8H14N4O6 |
Molecular Weight | 262.22 g/mol |
InChI | InChI=1S/C8H14N4O6/c9-12-10-1-4(14)11-5-7(16)6(15)3(2-13)18-8(5)17/h3,5-8,13,15-17H,1-2H2,(H,11,14) |
InChI Key | AFNOHTDETQTADW-UHFFFAOYSA-N |
SMILES | C(C1C(C(C(C(O1)O)NC(=O)CN=[N+]=[N-])O)O)O |
Canonical SMILES | C(C1C(C(C(C(O1)O)NC(=O)CN=[N+]=[N-])O)O)O |
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