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37-87-6 , Naphthol AS-BI-beta-D-glucuronic acid

37-87-6 , Naphthol AS-BI-beta-D-glucuronic acid,
Cas:37-87-6
C24H22BrNO9 / 548.35
MFCD00067162

Naphthol AS-BI-beta-D-glucuronic acid

Naphthol AS-BI b-D-glucuronide is an enzyme inhibitor that inhibits phosphatases, which are enzymes that hydrolyze phosphate esters. It can be used as a marker enzyme to identify cells in lymphocytic leukemia and cancer. Naphthol AS-BI b-D-glucuronide can be used to stain cells in histochemical staining. It was also shown to inhibit the growth of acute lymphoblastic leukemia (ALL) animals and chronic lymphocytic leukemia (CLL) in mice.

2-naphthol AS BI-beta-D-glucuronide (NAG) is a glucuronide ester of 2-naphthol, which is commonly used as a reagent in the enzymatic determination of beta-glucuronidase activity. NAG has unique physical and chemical properties, and it has been the topic of numerous research studies due to its potential applications in a variety of fields.

CAS Number37-87-6
Product Name2-naphthol AS BI-beta-D-glucuronide
IUPAC Name(2S,3S,4S,5R,6S)-6-[6-bromo-3-[(2-methoxyphenyl)carbamoyl]naphthalen-2-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
Molecular FormulaC24H22BrNO9
Molecular Weight548.3 g/mol
InChIInChI=1S/C24H22BrNO9/c1-33-16-5-3-2-4-15(16)26-22(30)14-9-12-8-13(25)7-6-11(12)10-17(14)34-24-20(29)18(27)19(28)21(35-24)23(31)32/h2-10,18-21,24,27-29H,1H3,(H,26,30)(H,31,32)/t18-,19-,20+,21-,24+/m0/s1
InChI KeyACOOAEDFQKSZTC-UHFFFAOYSA-N
SMILESCOC1=CC=CC=C1NC(=O)C2=C(C=C3C=CC(=CC3=C2)Br)OC4C(C(C(C(O4)C(=O)O)O)O)O
Canonical SMILESCOC1=CC=CC=C1NC(=O)C2=C(C=C3C=CC(=CC3=C2)Br)OC4C(C(C(C(O4)C(=O)O)O)O)O


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