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488-81-3 , Adonitol, Ribitol, CAS:488-81-3

488-81-3, Adonitol,Ribitol,
CAS:488-81-3
C5H12O5 / 152.15
MFCD00064291

核糖醇, Ribitol

Ribitol is a pentose sugar alcohol derived from ribose in vivo via the pentose phosphate pathway. It is a component of the glycopolymer teichoic acid in bacterial cell walls. Levels of ribitol are increased in the brain, cerebrospinal fluid, urine, and plasma of a patient with ribose-5-phosphate isomerase (RPI) deficiency, an extremely rare inborn error of metabolism characterized by a heterozygous frameshift mutation and missense allele in the RPI gene leading to leukoencephalopathy and mild peripheral polyneuropathy.


Title: Adonitol

CAS Registry Number: 488-81-3

CAS Name: Ribitol

Additional Names: adonite

Molecular Formula: C5H12O5

Molecular Weight: 152.15

Percent Composition: C 39.47%, H 7.95%, O 52.58%

Literature References: A pentitol from Adonis vernalis L., Ranunculaceae; also from A. amurensis L., Ranunculaceae: Santavy, Reichstein, Pharm. Acta Helv. 23, 153 (1948).

Properties: Large, optically inactive crystals. mp 102°. Does not reduce Fehling's soln. Freely soluble in water, hot alcohol; insol in ether.

Melting point: mp 102°

CAS Number488-81-3
Product NameRibitol
IUPAC Name(2S,4R)-pentane-1,2,3,4,5-pentol
Molecular FormulaC5H12O5
Molecular Weight152.15
InChIInChI=1S/C5H12O5/c6-1-3(8)5(10)4(9)2-7/h3-10H,1-2H2/t3-,4+,5?
InChI KeyHEBKCHPVOIAQTA-ZXFHETKHSA-N
SMILESC(C(C(C(CO)O)O)O)O
SolubilitySoluble in DMSO
SynonymsRibitol, Adonitol, NSC 16868


CAS No: 488-81-3 Synonyms: Adonitol MDL No: MFCD00064291 Chemical Formula: C5H12O5 Molecular Weight: 152.15IN Stock.现货
COA:

Product name: AdonitolRibitol   CAS: 488-81-3    M.F.: C5H12O5        M.W.: 152.15

Items

Standards

Results

Appearance

A white solid

Positive

Solubility

Easily soluble in H2O and

less soluble in petroleum ether

Complies

Appearance of solution

Dissolve 0.5 gin 10 ml of water,

and the solution should be clear

Complies

NMR and ESI-MS

Should comply

Complies

Identification

IR and TLC

Positive

M.P.

100℃ - 102

100℃ - 102

Residue on ignition

Max. 0.5%

0.05%

Heavy metal

Max. 20ppm

Complies

TLC (15%H2SO4-C2H5OH)

One spot

Complies

Assay

Min. 98%

99.2%

References:

1. de Valdéz GF, de Giori GS, de Ruiz Holgado AAP, Oliver G, Appl. Environ. Microbiol. 1983, p302–304


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