71812-11-8 , Fucosyl-GM1 ganglioside , Fucosylated monosialoganglioside GM1

71812-11-8 , Fucosyl-GM1 ganglioside , Fucosylated monosialoganglioside GM1
C79H141N3O35 / 1692.96

Fucosyl-GM1 ganglioside , Fucosylated monosialoganglioside GM1

Monosialylated glycosphingolipid with an α1,2-fucosylated galactose at the nonreducing end. The moluecule is minimally expressed in healthy tissues but has high prevalence in some tumours such as small cell lung cancer (SCLC). Fucosyl-GM1 ganglioside is a potential tumour marker for SCLC and a potential antigen target for immunotherapy.

CAS Number	71812-11-8
Product Name	Fuc-alpha1,2gal-beta1,3galnac-beta1,4(neu5AC-alpha2,3)gal-beta1,4glc-beta1,1 ceramide, NH4, bovine
IUPAC Name	azanium;(2S,4S,5R,6R)-5-acetamido-2-[(2S,3R,4R,5S,6R)-5-[(2S,3R,4R,5R,6R)-3-acetamido-4-[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[(2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(E,2S,3R)-3-hydroxy-2-(octadecanoylamino)octadec-4-enoxy]oxan-3-yl]oxy-3-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate
Molecular Formula	C79H141N3O35·NH3
Molecular Weight	1693 + NH3 (stearoyl)
InChI	InChI=1S/C79H141N3O35.H3N/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-54(93)82-46(47(90)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2)42-106-74-65(102)63(100)67(52(40-86)110-74)112-76-66(103)71(117-79(78(104)105)36-48(91)55(80-44(4)88)70(116-79)58(95)49(92)37-83)68(53(41-87)111-76)113-73-56(81-45(5)89)69(60(97)51(39-85)108-73)114-77-72(62(99)59(96)50(38-84)109-77)115-75-64(101)61(98)57(94)43(3)107-75;/h32,34,43,46-53,55-77,83-87,90-92,94-103H,6-31,33,35-42H2,1-5H3,(H,80,88)(H,81,89)(H,82,93)(H,104,105);1H3/b34-32+;/t43-,46+,47-,48+,49-,50-,51-,52-,53-,55-,56-,57+,58-,59+,60+,61+,62+,63-,64-,65-,66-,67-,68+,69-,70-,71-,72-,73+,74-,75-,76+,77+,79+;/m1./s1
SMILES	CCCCCCCCCCCCCCCCCC(=O)NC(COC1C(C(C(C(O1)CO)OC2C(C(C(C(O2)CO)OC3C(C(C(C(O3)CO)O)OC4C(C(C(C(O4)CO)O)O)OC5C(C(C(C(O5)C)O)O)O)NC(=O)C)OC6(CC(C(C(O6)C(C(CO)O)O)NC(=O)C)O)C(=O)[O-])O)O)O)C(C=CCCCCCCCCCCCCC)O.[NH4+]
Synonyms	Fucosyl-GM1