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852311-55-8 , 6-a-D-Glucopyranosylmaltotriose tetradecaacetate

852311-55-8 , 6-a-D-Glucopyranosylmaltotriose tetradecaacetate ,
Glc1-a-6Glc1-a-4Glc1-a-4Glc decatetraacetate;
O-2,3,4,6-Tetra-O-acetyl-a-D-glucopyranosyl-(16)-O-2,3,4-tri-O-acetyl-a-D-glucopyranosyl-(14)-O-2,3,6-tri-O-acetyl-a-D-glucopyranosyl-(14)-D-glucopyranose tetraacetate
Cas:852311-55-8
C52H70O35 / 1255.09
MFCD09840667

6-a-D-Glucopyranosylmaltotriose tetradecaacetate , 

Glc1-a-6Glc1-a-4Glc1-a-4Glc decatetraacetate; 

O-2,3,4,6-Tetra-O-acetyl-a-D-glucopyranosyl-(16)-O-2,3,4-tri-O-acetyl-a-D-glucopyranosyl-(14)-O-2,3,6-tri-O-acetyl-a-D-glucopyranosyl-(14)-D-glucopyranose tetraacetate

6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate is a non-toxic and non-immunogenic sugar-based compound with broad applications in various fields of research and industry. This compound belongs to the family of maltodextrin derivatives, which are widely used as excipients in pharmaceutical and food industries due to their excellent properties such as solubility, low viscosity, and biodegradability. The aim of this paper is to provide a comprehensive overview of 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate, including its definition, physical and chemical properties, synthesis and characterization, analytical methods, biological properties, toxicity and safety in scientific experiments, applications in scientific experiments, current state of research, potential implications in various fields of research and industry, limitations, and future directions.

Physical and Chemical Properties

6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate is a white crystalline powder that is soluble in water and organic solvents such as ethanol and acetone. It has a melting point of 147-150°C and a specific rotation of +34.0 to +36.0°. The compound is stable at room temperature and slowly hydrolyzes in aqueous solutions at pH 7.

Synthesis and Characterization

The synthesis of 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate is achieved by modifying maltotriose with acetic anhydride in the presence of pyridine as a catalyst under alkaline conditions. The reaction is carried out at room temperature for several hours until the desired product is obtained. The resulting product is purified by column chromatography and characterized by various analytical methods such as NMR, FT-IR, and MS.

Analytical Methods

Various analytical methods are used to characterize and quantify 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate in different samples. These methods include HPLC, GC, NMR, FT-IR, and MS. HPLC is the most commonly used method for the separation and quantification of 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate due to its high sensitivity and resolution.

Biological Properties

6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate has various biological properties such as antioxidant, anti-inflammatory, and immunostimulatory activities. It has been reported to protect against oxidative stress-induced damage, reduce pro-inflammatory cytokine production, and enhance macrophage phagocytic activity. These properties make it a potential candidate for the development of novel therapeutics and nutraceuticals.

Toxicity and Safety in Scientific Experiments

Studies on the toxicity and safety of 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate in scientific experiments have shown that it is non-toxic and safe for consumption in humans and animals. It does not cause any adverse effects on various physiological and biochemical parameters such as liver and kidney function, blood parameters, and histopathology.

Applications in Scientific Experiments

6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate has various applications in scientific experiments such as drug delivery, gene therapy, tissue engineering, and diagnostic imaging. Due to its excellent biocompatibility, biodegradability, and low toxicity, it has been extensively studied as a potential drug carrier for targeted delivery of therapeutic agents to specific sites in the body.

Current State of Research

Research on 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate is still in its early stages, and many potential applications are yet to be explored. However, the compound has shown promising results in various preclinical studies, indicating its potential as a versatile biomaterial with broad applications in various fields of research and industry.

Potential Implications in Various Fields of Research and Industry

6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate has various implications in different fields of research and industry such as pharmaceuticals, food, biotechnology, cosmetics, and agriculture.

Limitations and Future Directions

Despite its promising properties, 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate has some limitations that need to be addressed in future research. For instance, the synthesis of this compound is a complex and expensive process, which may limit its large-scale production. Additionally, more in vivo studies are needed to fully understand the pharmacokinetics and pharmacodynamics of this compound, which will enable its translation into clinical practice. Nevertheless, the potential applications of 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate in various fields of research and industry make it an exciting compound to study, with broad implications for future development of novel therapeutics and biomaterials.

Future Directions

1. Development of novel drug delivery systems using 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate as a carrier.

2. Exploration of the anti-cancer properties of 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate.

3. Development of novel functional foods and nutraceuticals using 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate as an additive.

4. Study of the potential applications of 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate in tissue engineering and regenerative medicine.

5. Investigation of the impact of 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate on the gut microbiome and its potential as a prebiotic.

6. Study of the effects of 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate on different types of cancer cells in vitro and in vivo.

7. Development of novel wound healing and tissue regeneration therapies using 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate.

8. Study of the effect of 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate on immune system function and its potential as an immunomodulatory agent.

9. Development of nanoparticle-based drug delivery systems using 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate.

10. Investigation of the potential of 6-alpha-D-Glucopyranosylmaltotriose tetradecaacetate as a diagnostic imaging agent for various diseases.

CAS Number852311-55-8
Product Name6-alpha-D-Glucopyranosylmaltotriose Tetradecaacetate
IUPAC Name[(3R,4S,5S,6S)-4,5-diacetyloxy-6-[[(3R,4S,5S,6S)-3,4,5,6-tetraacetyloxyoxan-2-yl]methoxy]-3-[(2R,3S,4S,5R)-3,4,5-triacetyloxy-6-[[(2S,3S,4S,5R)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyoxan-2-yl]methyl acetate
Molecular FormulaC₅₂H₇₀O₃₅
Molecular Weight1255.09
InChIInChI=1S/C52H70O35/c1-19(53)67-15-33-37(71-21(3)55)41(74-24(6)58)45(78-28(10)62)49(83-33)70-18-36-39(73-23(5)57)43(76-26(8)60)48(81-31(13)65)52(86-36)87-40-34(16-68-20(2)54)84-50(46(79-29(11)63)44(40)77-27(9)61)69-17-35-38(72-22(4)56)42(75-25(7)59)47(80-30(12)64)51(85-35)82-32(14)66/h33-52H,15-18H2,1-14H3/t33?,34?,35?,36?,37-,38-,39-,40-,41+,42+,43+,44+,45+,46+,47+,48+,49+,50+,51-,52-/m1/s1
SMILESCC(=O)OCC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C)OC3C(C(C(C(O3)COC4C(C(C(C(O4)COC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C
SynonymsGlc1-α-6Glc1-α-4Glc1-α-4Glc Decatetraacetate; O-2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl-(16)-O-2,3,4-tri-O-acetyl-α-D-glucopyranosyl-(14)-O-2,3,6-tri-O-acetyl-α-D-glucopyranosyl-(14)-D-glucopyranose Tetraacetate;


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