L-Glucose, L-葡萄糖

L-glucose is a monosaccharide that is an important source of energy for the human body. The glucose molecule consists of 6 carbon atoms, 12 hydrogen atoms and 6 oxygen atoms. Glucose enters cells with the help of insulin and ATP-sensitive potassium channels. It has been shown that L-glucose can inhibit viral replication in vitro, such as HIV and herpes simplex virus type 1 (HSV-1). L-Glucose may be used to treat squamous carcinoma by reducing the redox potential in cancer cells. L-Glucose inhibits the growth of c. glabrata by inhibiting transcription activators and enzymes involved in glycolysis. L-Glucose also has hypoglycemic effects on humans by reducing cortisol concentrations in human serum.

What is L -(-)-Glucose exactly?

L -(-)-Glucose also can be described as a monosaccharide and an essential body energy source. The glucose molecule has six carbon atoms. 12 hydrogen atoms are included, and six oxygen. L -(-)-Glucose (also known as L-Glucose) is the L-isomer for glucose. It is the enantiomer for the more commonly used D-glucose. L -(-)-Glucose can be synthesized in the laboratory but is not found naturally in higher-living organisms. L -(-)-Glucose tastes identical to D-glucose. However, living organisms can't use it as a source of energy because it cannot be made phosphorylated with hexokinase. L -(-)-Glucose also could be used as a diagnostic aid.

L Glucose, an enantiomer of the more common D–glucose, is also known as L Glucose. L-Glucose can't be phosphorylated with hexokinase, so it isn't bioavailable as an energy source. However, it has been discovered that certain L-glucose-using bacteria contain NAD+ dependent L-glucose dehydrogenases, which can oxidize L-glucose.

Uses of L -(-)-Glucose

L -(-)-Glucose is a low-calorie sweetener that was once suggested. It is safe for people with diabetes mellitus.

L -(-)-Glucose pentaacetate (an acetate derivative L -(-)-Glucose) was shown to stimulate insulin and could therefore help treat type 2 diabetes. L -(-)-Glucose also proved to be a laxative. It also was suggested as a colon cleaning agent that would not disrupt fluid or electrolyte concentrations associated with large quantities of poor-tasting osmotic bowel laxatives commonly used in preparation for colonoscopy.

Biological activity of L-(−)-Glucose

L -(-)-Glucose doesn't naturally occur in living organisms. However, it can be synthesized in the laboratory. L -(-)-Glucose tastes the same as d-glucose. However, it can't be used by living organisms to provide energy. It cannot be phosphorylated using hexokinase, the first glycolysis enzyme. Burkholderia cayophylli, an herb pathogenic bacterium that causes plant-related illnesses, is one exception. It contains the enzyme d-threoaldose 1-dehydrogenase. This enzyme is capable of oxidizing the L Glucose.

Mechanism of action of L-(−)-Glucose

L -(-)-Glucose enters cells via insulin and ATP-sensitive potassium channels. L-glucose is capable of inhibiting viral replication in vitro. This includes HIV and herpes Simplex virus type 1 (HSV-1). L-Glucose could be used to treat squamous tumors by reducing the redox activity in cancer cells. L-Glucose inhibits c. glabrata growth by blocking transcription activators and enzymes involved in glycolysis.

L Glucose, an enantiomer of the more common D–glucose, is also known as L Glucose. Cells cannot use L-Glucose to provide energy because it isn't phosphorylated by hexokinase.C

Chemical properties of L-(−)-Glucose

L -(-)-Glucose also can be described as an organic compound having the formula C6H12O6/O=CH[CH(OH),)5H. It is precisely one of the aldohexose monosaccharides. It is the enantiomer for the more popular d-glucose, and it is also known as the isomer of glucose.

Like the D-isomer, glucose also can be found in one of four cyclic structural Iomers: a-, b-glucopyranose (the commonest, with a 6-atom ring), or a-, b-glucopyranose (with a 5-atom ring). These isomers convert in just a few hours using the open chain as an intermediate step.