132854-36-5, a-Naphthyl phosphate disodium salt hydrate

132854-36-5, a-Naphthyl phosphate disodium salt hydrate;
1-Naphthalenol dihydrogen phosphate disodium salt; 1-Naphthyl disodium orthophosphate,
Cas:132854-36-5
C10H7O4PNa2 / 268.11(as anhydrous)
MFCD00041007

a-Naphthyl phosphate disodium salt hydrate

1-Naphthalenol dihydrogen phosphate disodium salt; 1-Naphthyl disodium orthophosphate

a-Naphthyl phosphate disodium salt hydrate (APDS) is a potent inhibitor of phosphatases, which are enzymes that catalyze the hydrolysis of phosphoric acid esters. APDS inhibits the formation rate of polyphosphate in cells and has been shown to inhibit the mineralization of bone by osteoclasts. APDS binds to polyphosphate and prevents its polymerization, inhibiting cell growth. This drug also inhibits enzyme activity in biological products such as DNA and RNA polymerases, ribosomes, and histidine decarboxylase.

CAS Number	132854-36-5
Product Name	Sodium naphthalen-1-yl phosphate hydrate
Molecular Formula	C10H11Na2O5P
Molecular Weight	288.146
InChI	InChI=1S/C10H9O4P.2Na.H2O/c11-15(12,13)14-10-7-3-5-8-4-1-2-6-9(8)10;;;/h1-7H,(H2,11,12,13);;;1H2
InChI Key	ITDOXWAUHXVEJT-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C=CC=C2OP(=O)(O)O.O.[Na].[Na]