2044-85-1; 2',7'-Dichlorofluorescein diacetate; H2DCFDA; MFCD 37501; DCDHF DIACETATE; DIACETYLDICHLOROFLUORESCIN

Cas:2044-85-1;
2',7'-Dichlorofluorescein diacetate;
H2DCFDA;
MFCD 37501;
DCDHF DIACETATE;
DIACETYLDICHLOROFLUORESCIN
C24H14Cl2O7 / 485.27
MFCD00037501

双氯荧光黄乙酸乙酯 ,H2DCFDA 2',7'-Dichlorofluorescein diacetate

Fluorogenic probe used for the detection of reactive oxygen species

2',7'-Dichlorofluorescein diacetate is as a cell-permeable fluorogenic probe to quantify reactive oxygen species (ROS) and nitric oxide (NO). It is rapidly de-esterified in cells is oxidized to form fluorescent 2',7'-dichlorofluorescein. 2'7-Dichlorofluorescein displays excitation/emission spectra of 492/515 nm.

Diacetyldichlorofluorescein is the stable storage form of dichlorofluorescein.

CAS Number	2044-85-1
Product Name	Diacetyldichlorofluorescein
IUPAC Name	(6'-acetyloxy-2',7'-dichloro-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl) acetate
Molecular Formula	C24H14Cl2O7
Molecular Weight	485.3 g/mol
InChI	InChI=1S/C24H14Cl2O7/c1-11(27)30-21-9-19-15(7-17(21)25)24(14-6-4-3-5-13(14)23(29)33-24)16-8-18(26)22(31-12(2)28)10-20(16)32-19/h3-10H,1-2H3
InChI Key	VQVUBYASAICPFU-UHFFFAOYSA-N
SMILES	CC(=O)OC1=C(C=C2C(=C1)OC3=CC(=C(C=C3C24C5=CC=CC=C5C(=O)O4)Cl)OC(=O)C)Cl
Solubility	Soluble in DMSO
Synonyms	2',7'-dichlorofluorescein diacetate, 2',7'-dichlorofluorescin diacetate, 2',7'-difluorofluorescein, DCFDA, DCFH-DA, diacetyldichlorofluorescein, leuco-DCF diacetate, leukodiacetyl-2,7-dichlorofluorescein
Canonical SMILES	CC(=O)OC1=C(C=C2C(=C1)OC3=CC(=C(C=C3C24C5=CC=CC=C5C(=O)O4)Cl)OC(=O)C)Cl