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  • 3083-77-0 , 阿糖尿苷, Arabinofuranosyluracil, CAS:3083-77-0
  • 3083-77-0 , 阿糖尿苷, Arabinofuranosyluracil, CAS:3083-77-0
3083-77-0 , 阿糖尿苷, Arabinofuranosyluracil, CAS:3083-77-03083-77-0 , 阿糖尿苷, Arabinofuranosyluracil, CAS:3083-77-0

3083-77-0 , 阿糖尿苷, Arabinofuranosyluracil, CAS:3083-77-0

3083-77-0, 阿糖尿苷,
Arabinofuranosyluracil,
CAS:3083-77-0
C9H12N2O6 / 244.201
MFCD00065998

阿糖尿苷, Arabinofuranosyluracil

Ara-C is a cytotoxic anti-cancer drug that acts as an equilibrative nucleoside and inhibits DNA synthesis by blocking the enzyme arabinoside kinase. Ara-C is used in the treatment of human malignancies, including lymphocytic leukemia and other leukemias. Ara-C has been shown to be effective in low doses against squamous cell carcinoma. This drug also interacts with other drugs, so it should not be taken with drugs such as ara-c or chloramphenicol.

CAS Number3083-77-0
Product NameSpongouridine
IUPAC Name1-[(3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Molecular FormulaC9H12N2O6
Molecular Weight244.2 g/mol
InChIInChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7+,8?/m1/s1
InChI KeyDRTQHJPVMGBUCF-CCXZUQQUSA-N
SMILESC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
SolubilitySoluble in DMSO
Synonyms1 beta D Arabinofuranosyl Uracil, 1-beta-D-Arabinofuranosyl Uracil, Ara U, Ara-U, Arabinofuranoside, Uracil, Arabinofuranosyluracil, Arabinoside, Uracil, Arabinosyluracil, Arauridine, NSC 68928, Sponguridine, Uracil Arabinofuranoside, Uracil Arabinoside, Uracil, 1-beta-D-Arabinofuranosyl
Canonical SMILESC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
Isomeric SMILESC1=CN(C(=O)NC1=O)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O


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