55033-90-4 , Isorhamnetin-3-O-neohesperidoside;
Calendoflavoside,
Cas:55033-90-4
C28H32O16 / 624.54
MFCD11042252
Isorhamnetin-3-O-neohesperidoside ;
Calendoflavoside is a natural product that has cytotoxic and anti-cancer properties. It is a type of typhaneoside, which are a class of polysaccharides found in the bark of the genus Torreya. Calendoflavoside has been shown to induce apoptosis in colorectal adenocarcinoma cells by binding to the matrix metalloproteinase (MMP) and inhibiting its activity. This compound also inhibits phosphatases, which are enzymes that remove phosphate groups from other molecules. Calendoflavoside can be detected in urine samples due to its high water solubility, making it an excellent candidate for use as a marker of cancerous tissue. Calendoflavoside was found to have anticancer effects in animal studies. The antitumor effects were mediated via inhibition of protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division.
Calendoflavoside is a type of flavonoid that is present in various plants and has demonstrated potential in various scientific experiments. It was first identified in the petals of calendula officinalis, also known as pot marigold flower. Studies have shown that this compound has significant biological properties such as antioxidant, anti-inflammatory, antitumor, and immunomodulatory effects.
Synthesis and Characterization:
Calendoflavoside can be synthesized from various natural sources such as plants or plant extracts. Different isolation techniques such as solvent extraction, column chromatography, and semi-preparative HPLC are used to obtain this compound in its pure form. The characterization of calendoflavoside is usually performed using techniques such as NMR spectroscopy, mass spectrometry, and X-ray diffraction.
Analytical Methods:
Various analytical methods are used to determine the presence and concentration of calendoflavoside in different samples. Some of the commonly used methods are HPLC, UV-Vis spectroscopy, and TLC. These methods can be used for the qualitative and quantitative analysis of calendoflavoside.
Biological Properties:
Calendoflavoside exhibits various biological properties that make it a potential compound for different scientific experiments. It has been shown to have significant antioxidant, anti-inflammatory, antitumor, and immunomodulatory effects in vitro and in vivo studies. Calendoflavoside has also been found to have neuroprotective effects and can inhibit the growth of different types of cancer cells.
Toxicity and Safety in Scientific Experiments:
Studies have shown that calendoflavoside is relatively safe for use in scientific experiments. It has been found to have low toxicity and no adverse effects on the health of experimental animals. However, more research is needed to determine the long-term effects of calendoflavoside on human health.
Applications in Scientific Experiments:
Calendoflavoside has potential applications in various fields of research such as medicine, pharmaceuticals, and cosmetics. It can be used as a natural antioxidant and anti-inflammatory agent in various formulations. Calendoflavoside has also demonstrated potential as a chemopreventive and chemotherapeutic agent in cancer research.
Current State of Research:
Calendoflavoside is a compound that is currently being extensively studied for its potential benefits in medical research. Many studies have been conducted to understand its properties and functions. However, further research is necessary to determine the mechanisms of action and the full extent of the compound’s potential applications.
Potential Implications in Various Fields of Research and Industry:
Calendoflavoside has potential implications in various fields such as medicine, pharmaceuticals, and cosmetics. Its therapeutic applications can range from anti-inflammatory agents to chemotherapeutic agents. Calendoflavoside also has applications in the food and beverage industry as a natural food coloring agent.
Limitations and Future Directions:
Although calendoflavoside has shown potential in different scientific experiments, there are still limitations and challenges associated with its use. Further research is needed to fully understand the mechanisms of action and the full extent of its potential applications. Some of the future directions for research may include investigating the use of calendoflavoside in combination with other compounds to improve its efficacy and exploring potential new applications.
In conclusion, calendoflavoside is a potent flavonoid compound with potential applications in various scientific fields. Its properties and mechanisms of action make it a promising compound for future studies and investigations. Despite the current limitations, more extensive research is required to understand the full extent of its potential applications in various industries.
CAS Number | 55033-90-4 |
Product Name | Calendoflavoside |
IUPAC Name | 3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one |
Molecular Formula | C28H32O16 |
Molecular Weight | 624.54 g/mol |
InChI | InChI=1S/C28H32O16/c1-9-18(33)21(36)23(38)27(40-9)44-26-22(37)19(34)16(8-29)42-28(26)43-25-20(35)17-13(32)6-11(30)7-15(17)41-24(25)10-3-4-12(31)14(5-10)39-2/h3-7,9,16,18-19,21-23,26-34,36-38H,8H2,1-2H3/t9-,16+,18-,19+,21+,22-,23+,26+,27-,28-/m0/s1 |
InChI Key | QHLKSZBFIJJREC-SPSUIZEHSA-N |
SMILES | CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)OC)CO)O)O)O)O)O |
Synonyms | Isorhamnetin 3-O-Neohesperidoside; Isorhamnetin 3-O-Neohesperoside; 3-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; Calendoflavoside |
Canonical SMILES | CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)OC)CO)O)O)O)O)O |
Isomeric SMILES | C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)OC)CO)O)O)O)O)O |
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