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  • 5725-89-3 ,甲氧基试卤灵, Resorufin methyl ether ; 7-Methoxy-3H-phenoxazin-3-one;  7-Methoxyresorufin;  Resorufin 7-O-methyl ether
5725-89-3 ,甲氧基试卤灵, Resorufin methyl ether ; 7-Methoxy-3H-phenoxazin-3-one;  7-Methoxyresorufin;  Resorufin 7-O-methyl ether

5725-89-3 ,甲氧基试卤灵, Resorufin methyl ether ; 7-Methoxy-3H-phenoxazin-3-one; 7-Methoxyresorufin; Resorufin 7-O-methyl ether

5725-89-3 ,甲氧基试卤灵,
Resorufin methyl ether ;
7-Methoxy-3H-phenoxazin-3-one;
7-Methoxyresorufin;
Resorufin 7-O-methyl ether,
Cas:5725-89-3
C13H9NO3 / 227.22
MFCD00037663

Resorufin methyl ether,甲氧基试卤灵, 

7-Methoxy-3H-phenoxazin-3-one;

7-Methoxyresorufin;
Resorufin 7-O-methyl ether

Fluorogenic substrate used to differentiate cytochrome P450 monooxygenases.

Fluorometric competitive cytochrome P450 substrate. Resorufin butyrate analog. Shows selectivity for CYP1A (Ki = 20 μM, dealkylation 0.5 μM substrate).

Methoxyresorufin is a fluorogenic substrate for the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2.1,2,3 Methyoxyresorufin is O-demethylated by CYP1A1/2, releasing resorufin, which displays excitation/emission maxima of 570/580 nm, respectively. The appearance of resorufin fluorescence can be used to quantify CYP1A1/2 activity.

CAS Number5725-89-3
Product NameMethoxyresorufin
IUPAC Name7-methoxyphenoxazin-3-one
Molecular FormulaC13H9NO3
Molecular Weight227.22 g/mol
InChIInChI=1S/C13H9NO3/c1-16-9-3-5-11-13(7-9)17-12-6-8(15)2-4-10(12)14-11/h2-7H,1H3
InChI KeyKNYYMGDYROYBRE-UHFFFAOYSA-N
SMILESCOC1=CC2=C(C=C1)N=C3C=CC(=O)C=C3O2
Synonyms7-Methoxy-3H-phenoxazin-3-one; 7-Methoxyphenoxazone; Methoxyresorufin; O-Methylresorufin; Resorufin Methyl Ether
Canonical SMILESCOC1=CC2=C(C=C1)N=C3C=CC(=O)C=C3O2


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