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  • 7298-65-9,Fluorescein dibutyrate
7298-65-9,Fluorescein dibutyrate

7298-65-9,Fluorescein dibutyrate

7298-65-9,Fluorescein dibutyrate
C28H24O7 / 472.49
MFCD00037842

Fluorescein dibutyrate

Fluorogenic esterase and lipase substrate

Fluorescein dibutyrate is a pharmaceutical preparation that is used to treat certain types of cancer. It is a synthetic fluorophore that binds to DNA and RNA, which can be visualized by fluorescence microscopy. Fluorescein dibutyrate has been shown to inhibit the cellular production of ATP in human lymphocytes, as well as transposable elements in mouse erythrocytes. This agent has also been shown to inhibit protease activity in yeast cell extracts and to bind to nucleic acids with high affinity. Fluorescein dibutyrate is active against a variety of bacteria and fungi, including Escherichia coli, Pseudomonas aeruginosa, Candida albicans, Aspergillus fumigatus, Saccharomyces cerevisiae, Saccharomyces kluyveri and Schizosaccharomyces pombe.

CAS Number7298-65-9
Product NameFluorescein dibutyrate
IUPAC Name(6'-butanoyloxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl) butanoate
Molecular FormulaC28H24O7
Molecular Weight472.5 g/mol
InChIInChI=1S/C28H24O7/c1-3-7-25(29)32-17-11-13-21-23(15-17)34-24-16-18(33-26(30)8-4-2)12-14-22(24)28(21)20-10-6-5-9-19(20)27(31)35-28/h5-6,9-16H,3-4,7-8H2,1-2H3
InChI KeyCGMHIZMGYHYHML-UHFFFAOYSA-N
SMILESCCCC(=O)OC1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)OC(=O)CCC)C5=CC=CC=C5C(=O)O3
SynonymsFLUORESCEIN DIBUTYRATE;FLUORESCEIN DIBUTYRATE, FOR FLUOR-ESCENC E;Dibutanoic acid 3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl ester;Dibutyric acid 3'-oxospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3,6-diyl ester;Butanoic acid, 1,1
Canonical SMILESCCCC(=O)OC1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)OC(=O)CCC)C5=CC=CC=C5C(=O)O3


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