81028-91-3, D-Fructose 1,6-bisphosphate trisodium salt hydrate,
1,6-二磷酸果糖三钠盐(八水合物),
CAS:81028-91-3
C6H11Na3O12P2·8H2O / 550.18
MFCD00149340
D-Fructose-1,6-diphosphate trisodium salt octahydrate (DFP) is a metabolite that is produced during the breakdown of fructose. DFP has been shown to be an intermediate in the synthesis of ATP, which is necessary for the production of energy. DFP also plays a role in collagen and atp levels in heart tissue. It is used as a reagent to measure sodium citrate transport pathways and can be used as a marker for ventricular myocardium. DFP has synergistic effects with other compounds such as creatine, citric acid, and pyridoxine hydrochloride.
D-Fructose-1,6-bisphosphate is an intermediate in carbohydrate metabolism, including glycolysis and gluconeogenesis. During glycolysis, it is generated by the phosphorylation of fructose-6-phosphate by phosphofructokinase. The reverse reaction, mediated by fructose-1,6-bisphosphatase-1, is one of the rate-limiting steps in gluconeogenesis. The same reaction occurs within chloroplasts in plants as part of the reductive pentose phosphate cycle. Because cancer cells adopt glycolysis as a major source of metabolic energy production, this pathway has become a major target for cancer chemotherapy.
CAS Number | 81028-91-3 |
Product Name | Harden-Young ester |
IUPAC Name | trisodium;[(2R,3R,4S)-2,3,4-trihydroxy-6-[hydroxy(oxido)phosphoryl]oxy-5-oxohexyl] phosphate;octahydrate |
Molecular Formula | C6H11Na3O12P2·8H2O |
Molecular Weight | 550.18 |
InChI | InChI=1S/C6H14O12P2.3Na.8H2O/c7-3(1-17-19(11,12)13)5(9)6(10)4(8)2-18-20(14,15)16;;;;;;;;;;;/h3,5-7,9-10H,1-2H2,(H2,11,12,13)(H2,14,15,16);;;;8*1H2/q;3*+1;;;;;;;;/p-3/t3-,5-,6-;;;;;;;;;;;/m1.........../s1 |
InChI Key | SLINXSDQTXGTNN-OLMHPWOBSA-N |
SMILES | C(C(C(C(C(=O)COP(=O)(O)[O-])O)O)O)OP(=O)([O-])[O-].O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+] |
Synonyms | 1,6-bis(dihydrogen phosphate)-D-fructose, trisodium salt, octahydrate |
CAS No: 81028-91-3,38099-82-0 Synonyms: D-Fructose-1,6-bisphosphate trisodium salt octahydrate MDL No: MFCD00149340 Chemical Formula: C6H11Na3O12P2·8H2O Molecular Weight: 550.18 |
COA:
Product name: D-Fructose 1,6-bisphosphate trisodium salt hydrate
CAS: 81028-91-3 Batch No: 20130110 Quantity:560g
Items | Standards | Results |
Appearance | White crystal powder | Complies |
Solubility | Easily soluble in water, insoluble in CHCl3 | Complies |
NMR and MS | Should comply | Complies |
Identification | IR and TLC | Complies |
pH | 5.5 – 7.0 | 6.02 |
Free H3PO4 | Max. 0.5% | 0.12% |
Chlorides | Max. 0.03% | Complies |
Sulphates | Max. 0.05% | Complies |
Heavy metal | Max.10ppm | Complies |
Water | Max.30% | 24.5% |
Microorganisms | Should comply | Complies |
Assay | Min. 99% | 99.4% |
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