87190-79-2 , 3'-叠氮基-2',3'-二脱氧-5-甲基胞苷, Azddmec, CAS:87190-79-2

87190-79-2 , 3'-Azido-2',3'-dideoxy-5-methylcytidine,
CAS:87190-79-2
C10H14N6O3 / 266.257

Azddmec

3'-叠氮基-2',3'-二脱氧-5-甲基胞苷

3'-Azido-2',3'-dideoxy-5-methylcytidine

Azddmec is a microorganism-derived antibiotic that has been shown to have potent antimicrobial activity. It is derived from the microorganism Streptomyces sp. and belongs to the class of macrolides. Azddmec has been shown in vitro to have broad-spectrum antibacterial activity, including against Gram-positive bacteria such as Staphylococcus aureus, Enterococcus faecalis, and Bacillus subtilis, as well as Gram-negative bacteria such as Escherichia coli and Pseudomonas aeruginosa. In addition, it has been shown to be active against some mycobacteria species that are resistant to other antibiotics.

Az-Dcme, also known as CS-92; AzddMeC; Azidodideoxymethylcytidine, is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection.

CAS Number	87190-79-2
Product Name	3'-Azido-2',3'-dideoxy-5-methylcytidine
IUPAC Name	4-amino-1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidin-2-one
Molecular Formula	C10H14N6O3
Molecular Weight	266.257 g/mol
InChI	InChI=1S/C10H14N6O3/c1-5-3-16(10(18)13-9(5)11)8-2-6(14-15-12)7(4-17)19-8/h3,6-8,17H,2,4H2,1H3,(H2,11,13,18)/t6-,7+,8+/m0/s1
InChI Key	GZSDAHQGNUAEBC-XLPZGREQSA-N
SMILES	CC1=CN(C(=O)N=C1N)C2CC(C(O2)CO)N=[N+]=[N-]
Solubility	Soluble in DMSO
Synonyms	Az-Dcme; CS-92; AzddMeC; Azidodideoxymethylcytidine; 3'-Azido-2',3'-dideoxy-5-methylcytidine
Canonical SMILES	CC1=CN(C(=O)N=C1N)C2CC(C(O2)CO)N=[N+]=[N-]
Isomeric SMILES	CC1=CN(C(=O)N=C1N)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-]