89157-94-8 , Sodium (4-methylumbelliferyl a-L-idopyranosid)uronate; 4-Methylumbelliferyl a-L-idopyranosiduronic acid sodium salt;

89157-94-8 , Sodium (4-methylumbelliferyl a-L-idopyranosid)uronate;
4-Methylumbelliferyl a-L-idopyranosiduronic acid sodium salt;
Cas:89157-94-8
C16H15NaO9 / 374.27
MFCD09750655

Sodium (4-methylumbelliferyl a-L-idopyranosid)uronate

4-Methylumbelliferyl a-L-idopyranosiduronic acid sodium salt;

4MU-alpha-L-idopyranosiduronic acid is a fluorogenic substrate for alpha-L-iduronidase. Active alpha-L-iduronidase cleaves the MU moiety from the synthetic substrate, which results in release of a fluorescent signal (Ex 360 nm / Em 455 nm). The reaction is stopped by the addition of sodium carbonate. 4MU-alpha-L-idopyranosiduronic acid is used in alpha-L-iduronidase assays in the context of biochemical characterisation of samples from patients affected by lysosomal storage disease mucopolysaccharidosis I (MPS I).

CAS Number	89157-94-8
Product Name	Sodium (2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)tetrahydro-2H-pyran-2-carboxylate
IUPAC Name	sodium;3,4,5-trihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxane-2-carboxylate
Molecular Formula	C₁₆H₁₅NaO₉
Molecular Weight	374.27
InChI	InChI=1S/C16H16O9.Na/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22;/h2-5,11-14,16,18-20H,1H3,(H,21,22);/q;+1/p-1
SMILES	CC1=CC(=O)OC2=C1C=CC(=C2)OC3C(C(C(C(O3)C(=O)[O-])O)O)O.[Na+]
Synonyms	4-Methylumbelliferyl α-L-Iduronic Acid, Sodium Salt