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  • 95058-81-4 ,吉西他滨 ,Gemcitabine, CAS:95058-81-4
95058-81-4 ,吉西他滨 ,Gemcitabine, CAS:95058-81-4

95058-81-4 ,吉西他滨 ,Gemcitabine, CAS:95058-81-4

  • CAS:95058-81-4
  • C9H11F2N3O4 / 263.20
  • MFCD00869720
  • 产品描述:95058-81-4 ,吉西他滨 ,Gemcitabine, CAS:95058-81-4
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Gemcitabine base

CAS No:
95058-81-4
Synonyms:
2;-Deoxy-2',2'-difluorocytidine
4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
2'-Deoxy-2',2'-difluoro-D-cytidine
2',2'-Difluoro-2'-deoxycytidine
MDL No:
MFCD00869720
Chemical Formula:
C9H11F2N3O4
Molecular Weight:
263.20
Product Structure

COA:

Name: Gemcitabine   CAS: 95058-81-4     

M.F.C9H11F2N3O      M.W.263.20      

Items

Standards

Results

Appearance

White crystalline power

Positive

NMR and MS

Should comply

Complies

Identification

IR and HPLC

Positive

M.P.

224 -230

224 -226

Specific rotation

0.96% solution in ethanol

+68o ~ +74o

+73.6o

Cytosine

Max. 0.1%

0.01%

Alpha-Isomer

Max. 0.1%

0.01%

Total impurities

Max. 1%

0.2%

Loss Weight On Dryness

Max. 0.5%

0.12%

Residue On Ignition

Max. 0.2%

0.02%

Heavy metal

Max. 20ppm

Complies

Assay (HPLC)

Min. 98%

99.6%

References:
1. Grunewald R, Abbruzzese JL, Tarassoff P, Plunkett W, Cancer Chemotherapy and Pharmacology 1991, Vol27, No4, p258-262

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