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576-42-1, D-Saccharic acid, monopotassium salt, CAS:576-42-1

Potassium bisaccharate,
Potassium hydrogen saccharate,
D-​Saccharic acid monopotassium,
D-Saccharic acid, monopotassium salt,
CAS:576-42-1
C6H9KO8 / 248.229
MFCD00064208

D-葡萄糖二酸单钾盐, D-Saccharic acid

D-Saccharic acid potassium salt is present in plants and animals. It is produced by the chemical oxidation of glucose with nitric acid. D-Saccharic acid lowers cholesterol and has chemotherapeutic property. It also has antimutagenic activity.

D-Glucarate monopotassium is a pharmaceutical preparation that is used to inhibit the growth of bacteria. It inhibits the proliferation of cells by inhibiting fatty acid synthesis, which leads to decreased levels of cholesterol, and reduces the uptake of glucose. D-Glucarate monopotassium is also an oxidizing agent that converts uridine into uric acid and has been shown to have inhibitory properties against human cancer cells. D-Glucarate monopotassium can be used as an antioxidant for the prevention or treatment of chronic diseases such as atherosclerosis, diabetes, and cancer. This compound acts as an inhibitor for trypsin treatment on carbohydrates, preventing hydrolysis by this enzyme.

Potassium bisaccharate or potassium hydrogen alpha-D-glucopyranoside acid is a compound composed of a potassium salt and gluconic acid. Bisaccharates belong to a group of chemical compounds that contain two monosaccharide units linked by oxygen or another functional group. Potassium bisaccharate is a salt derived from glucose, and it has been used for several purposes, mainly as a reagent and buffer agent in scientific experiments.

Synthesis and Characterization

Potassium bisaccharate can be synthesized by reacting gluconic acid with potassium hydroxide. The reaction occurs in an aqueous solution at a temperature of 60-80°C. The resulting solution is then concentrated and allowed to crystallize, resulting in potassium bisaccharate crystals.

The characterization of potassium bisaccharate can be performed using different techniques, such as infrared spectroscopy, X-ray diffraction, and elemental analysis. These techniques allow the identification of the functional groups, crystal structure, and chemical composition of the compound.

Analytical Methods

Analytical methods for the determination of potassium bisaccharate in different matrices include spectrophotometry, chromatography, and electrophoresis. These methods rely on the specific properties of potassium bisaccharate, such as its absorbance at a specific wavelength or charge properties. These methods are crucial for the accurate quantification of potassium bisaccharate in different matrices.

Biological Properties

Potassium bisaccharate has shown several biological properties, such as antimicrobial and antitumor activities. The compound has been shown to inhibit the growth of different bacteria, such as Staphylococcus aureus and Escherichia coli. Potassium bisaccharate has also shown antitumor activity in different cancer cell lines, such as HeLa cells and MCF-7 cells.

Toxicity and Safety in Scientific Experiments

Potassium bisaccharate is generally considered safe for scientific experiments. The compound has a low toxicity, with an LD50 of >2000 mg/kg in rats. However, caution must be exercised when handling potassium bisaccharate, as it may cause skin and eye irritation.

Applications in Scientific Experiments

Potassium bisaccharate has several applications in scientific experiments, mainly as a reagent and buffer agent. It is used for the preparation of different types of buffers, such as phosphate and Tris buffers. Potassium bisaccharate is also used for the purification and crystallization of proteins.

Current State of Research

The current state of research on potassium bisaccharate focuses on its potential applications in different fields, such as medicine, biochemistry, and food sciences. Several studies have investigated the biological properties of potassium bisaccharate, such as its antimicrobial and antitumor activities. Other studies have focused on the synthesis and characterization of potassium bisaccharate and its derivatives.

Potential Implications in Various Fields of Research and Industry

Potassium bisaccharate has several potential implications in various fields of research and industry. In medicine, potassium bisaccharate could be used as a potential antimicrobial and antitumor agent. In biochemistry, potassium bisaccharate could be used for the purification and crystallization of proteins. In the food industry, potassium bisaccharate could be used as a natural preservative.

Limitations and Future Directions

Despite the potential applications of potassium bisaccharate, there are some limitations that need to be addressed. One of the limitations is the low solubility of potassium bisaccharate in water. This limits its use in aqueous solutions, such as biological assays. Future research could focus on the synthesis of potassium bisaccharate derivatives with improved solubility and biological properties. Other future directions could include investigating the potential applications of potassium bisaccharate in the fields of nanotechnology and biotechnology.

CAS Number576-42-1
Product NamePotassium bisaccharate
IUPAC Namepotassium;(2R,3R,4R,5S)-2,3,4,5,6-pentahydroxy-6-oxohexanoate
Molecular FormulaC6H9KO8
Molecular Weight248.23 g/mol
InChIInChI=1S/C6H10O8.K/c7-1(3(9)5(11)12)2(8)4(10)6(13)14;/h1-4,7-10H,(H,11,12)(H,13,14);/q;+1/p-1/t1-,2-,3-,4+;/m1./s1
InChI KeyUBYZGUWQNIEQMH-SBBOJQDXSA-M
SMILESC(C(C(C(=O)[O-])O)O)(C(C(=O)O)O)O.[K+]
Synonymspotassium hydrogen D-glucarate, potassium hydrogen glucarate
Canonical SMILESC(C(C(C(=O)[O-])O)O)(C(C(=O)O)O)O.[K+]
Isomeric SMILES[C@H]([C@@H]([C@H](C(=O)[O-])O)O)([C@@H](C(=O)O)O)O.[K+]

white to off-white crystallin powder.In Stock.现货


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